A team of neurologists, stem cell specialists and molecular biologists affiliated with several institutions in the U.S. and led by a group at Stanford University School of Medicine has found evidence that the root cause of Alzheimer's disease may be fat buildup in brain cells. The study is published in the journal Nature.

A team of neurologists, stem cell specialists and molecular biologists affiliated with several institutions in the U.S. and led by a group at Stanford University School of Medicine has found evidence that the root cause of Alzheimer’s disease may be fat buildup in brain cells. The study is published in the journal Nature.

  • bushparty@sh.itjust.worksEnglish
    212·
    8 months ago

    Alzheimer’s is beginning to be understood as Type 3 Diabetes and will be more and more commonly be known as such. Meat (and fat) is making us sicker than people realize but is also easy to cut out or cut back on.

    “Conclusions: Altogether, the results from these studies provide strong evidence in support of the hypothesis that AD represents a form of diabetes mellitus that selectively afflicts the brain.”

    Link 1: Alzheimer’s Disease Is Type 3 Diabetes–Evidence Reviewed: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769828/

    “In studies across 11 countries, fat consumption appeared to be most closely correlated with the prevalence of Alzheimer’s disease, with the lowest fat intake and Alzheimer’s rates in China to the highest fat intake and Alzheimer’s rates in the United States.”

    Link 2: Preventing Alzheimer’s Disease with Diet: https://nutritionfacts.org/blog/preventing-alzheimers-disease-diet/

    • Pulptastic@midwest.socialEnglish
      122·
      8 months ago

      Meat doesn’t cause it (correlation, not causation), excess sugar does.

      Meat is satiating, eating protein and fat make you feel full.

      Sugar causes fluctuations in insulin levels that make you hungry even when your caloric needs are met. Excess sugars go to the body’s reserves of glycogen until they are full, then they must be used or converted to fat for storage. This insulin-driven fat storage is the problem and the solution is to eat much less sugar to break the cycle. Allow your body to use your glycogen reserves so it has room to temporarily store the next meal rather than sending it to semi-permanent fat storage. Exercise helps this balance by using up reserves but “you can’t outrun your fork”.

      Edit: nutritionfacts exists explicitly to promote a plant-based diet. They may be a good source for information but that bias must be considered.

      https://nutritionfacts.org/about/

      We also disseminate fact-based information through social media on the benefits of a whole food, plant-based diet for wellness, disease prevention, healthy weight management, and longevity

      • 🦄🦄🦄@feddit.deEnglish
        28·
        8 months ago

        Meat is satiating, eating protein and fat make you feel full.

        Wrong. Volume makes you full.

        • Pulptastic@midwest.socialEnglish
          71·
          8 months ago

          That is oversimplified and it does not change my argument at all.

          Satiety is both physical and hormonal, so volume and fat can make you full but insulin can override that.

          I can eat way more volume of carrots than brisket because fat is satiating. A small portion of fatty meat makes me feel full even though my stomach volume is not nearly capacity.

          https://pubmed.ncbi.nlm.nih.gov/15767618/

          https://www.ncbi.nlm.nih.gov/books/NBK53550/

          A study has shown that oral stimulation with different fats by modified-sham-feeding (MSF) resulted in increased feelings of satiety compared with water in human subjects, with linoleic acid showing the strongest response (Smeets and Westerterp-Plantenga, 2006). On the other hand, sham feeding a high-fat cake increased food intake at the next meal compared to nonfat cake in restrained eaters (Crystal and Teff, 2006).

          Without any volume ingested, fat increases satiety but fat+sugar reduces it.